2020 74:18–28.ĭe van Lind Wijngaarden RA, van Rijn L, Hagen EC, et al. Furthermore, CD3 +CD4 + T cells counts and serum IgG and C4 levels were independent risk factors with infection in patients with newly diagnosed AAV. Patients of infected AAV and those without infection differ in T lymphocyte subsets and immunoglobulin and complement levels. ![]() ![]() The levels of CD3 +CD4 + T cells (adjusted OR 0.997, P = 0.018), IgG (adjusted OR 0.804, P = 0.004), and C4 (adjusted OR 0.001, P = 0.013) were found independently associated with infection. 0.27 g/L, P < 0.001) were significantly lower in the infected group than in the noninfected group. The average levels of CD3 + T cells (720.0 vs. ResultsĢ80 patients with newly diagnosed AAV were enrolled. Further, regression analysis was conducted to determine the association of each variable with the risk of infection. The T lymphocyte subsets, immunoglobulin, and complement levels of the groups were compared between infected group and the noninfected group. ![]() The aim of this study was to characterize the immunological features of infectious events occurring in patients with newly diagnosed AAV and to identify possible risk factors associated with infection. ![]() Infection is the leading cause of death in patients with antineutrophil cytoplasmic antibody-associated vasculitis (AAV).
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